Pharmacy Practice Research Symposium Abstracts: 2004 AFPC Conference

Basic Research

1. BasicRes No. 1: ABC transporters as a key determinant of sex-related differences in drug-induced Long QT syndrome
   Pierre Morissette, Jacques Turgeon Faculté de pharmacie, Universite de Montreal
2. BasicRes No. 2: The effect of modulating glucuronidation on VPA-associated 8-iso-prostaglandin F2? levels in rats.
   Vincent Tong, Xiaowei Teng, Thomas K.H. Chang and Frank S. Abbott Faculty of Pharmaceutical Sciences, University of British Columbia
3. BasicRes No. 3: Postnatal maturation of cytochrome P450 2E1 and glutathione-S-transferases, pharmacokinetic model validation
   Fawzy A. Elbarbry, Jane Alcorn
   College of Pharmacy and Nutrition, University of Saskatchewan
4. BasicRes No. 4: Heat treated fungizone^® (HFZ) maintains amphotericin B’s (AmB) antifungal activity while decreasing its renal cytotoxicity: role of fungal phospholipases
   Erin Chew, Stephen D. Lee, Nancy S. Chung and Kishor M. Wasan
   Faculty of Pharmaceutical Sciences, University of British Columbia
5. BasicRes No. 5: Changes in gene expression of natriuretic peptides and myosin heavy chain isoforms in cardiomyopathic hamsters after treatment with growth hormone.
   Mukandila Mulumba, Huy Ong and Sylvie Marleau
   Faculty of Pharmacy, Université de Montréal
6. BasicRes No. 6: Mechanisms involved in the modulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factor-? and lipopolysaccharide
   Negar Gharavi and Ayman O.S. El-Kadi
   Faculty of Pharmacy, University of Alberta
7. BasicRes No. 7: Cytokine-mediated regulation of the rat mdr1b promoter in Huh7 hepatoma cells
   Emmanuel Ho and Micheline Piquette-Miller
   Department of Pharmaceutical Sciences, University of Toronto
8. BasicRes No. 8: Effect of warfarin on haloperidol lipoprotein and protein association within normolipidemic and hyperlipidemic human plasma
   Tiffany Ho¹, Ric M. Procyshyn^1,2 and Kishor M. Wasan^{1
   1}Faculty of Pharmaceutical Sciences, University of British Columbia, ²Riverview Hospital, British Columbia
9. BasicRes No. 9: Electrophysiological characterization of mutations found in the gene Kv1.5 in patients with different forms of atrial fibrillation
   Isabelle Plante¹, Dominique Fournier¹, Chantal Guillemette², Gilles O’Hara¹, Jean Champagne¹, Patrick Mathieu¹, Richard Baillot¹, Pascal Daleau^{1,2
   1}Quebec Heart Institute, Laval Hospital, ²Faculty of Pharmacy, Laval University
10. BasicRes No. 10: Study on the correlation of drug dissolution and polymer swelling from a matrix tablet using texture analyzer
    Hongtao Li, Xiaochen Gu
    Faculty of Pharmacy, University of Manitoba
11. BasicRes No. 11: Pharmacokinetic study of methotrexate loaded poly(L-lactic acid) microspheres following intra-articular injection in rabbits
    Linda Liang, Wesley Wong, and Helen Burt
    Faculty of Pharmaceutical Sciences, University of British Columbia
12. BasicRes No. 12: In vitro and in vivo percutaneous permeation of insect repellent N, N-Diethyl-m-toluamide (DEET) and sunscreen oxybenzone
    Sreeneeranj Kasichayanula, Xiaochen Gu
    Faculty of Pharmacy, University of Manitoba
13. BasicRes No. 13: 3-Hydroxy-4,9-dihydro-isothiazolo[5,4-b]quinoline-4-ones as topo-II inhibitors with antitumor activity
    Zohreh Amoozgar and Mohsen Daneshtalab
    School of Pharmacy, Memorial University of Newfoundland

Clinical Research

1. ClinRes No. 1: Optimizing care of diabetes patients with Ischemic heart disease at Burnaby Hospital
   

   Wendy A. Leong^*†, Lorna S. Leckie^†, Marshall Dahl^{*
   †}Burnaby Hospital; ^*University of British Columbia

2. ClinRes No. 2: Validation of logistic regression models for the development of thrombocytopenia in critical care patients.
   Arun K. Verma¹; Marc Levine^1,2; Stephen J. Shalansky^1,3; John J. Spinelli⁴ and Peter M. Dodek^{5
   1}Faculty of Pharmaceutical Sciences, University of British Columbia; ²Children’s & Women’s Health Centre of B.C.; ³Pharmacy Department, St. Paul’s Hospital; ⁴B.C. Cancer Agency; ⁵Critical Care Medicine, St. Paul’s Hospital and University of British Columbia
3. ClinRes No. 3: Phenotypic strategies, a better approach for individualized warfarin therapy
   Véronique Michaud, Denis Brouillette, Denis Roy, Lucie Verret, Nicolas Noel, Isabelle Taillon, Gilles O’Hara, Denis Gossard, Monique Champagne, Marie-Claude Vanier, Jacques Turgeon
   Faculté de pharmacie, Université de Montréal, Institut de cardiologie de Montréal, Institut de cardiologie de Québec, Hôpital Haut-Richelieu, Hôpital Maisonneuve-Rosemont, Xanthus Life Sciences
4. ClinRes No. 4: Evaluation of mitoxantrone in secondary progressive multiple sclerosis (SPMS)
   M. Namaka, M. Melanson, J. Major, L. Klassen, S. Slobodian, D. Ruhlen
   Faculty of Pharmacy, University of Manitoba
5. ClinRes No. 5: A novel genotyping algorithm for the CYP2D6*10 allele in Asians using real-time rapid-cycle PCR and multiplex PCR
   Evan H. Kwong¹, Marc Levine¹, Carolyne J. Montgomery², and Thomas K.H. Chang^{1
   1}Faculty of Pharmaceutical Sciences, University of British Columbia; ²Department of Anesthesiology, Children’s and Women’s Health Centre of British Columbia

Educational and Teaching Research

1. Edu/Teach No. 1: Anticoagulation training and certification in Canada
   Wendy A. Leong and The Anticoagulation Resource Team
   Burnaby Research and University of British Columbia
2. Edu/Teach No. 2: Self-care Curriculum Revitalized: The Experience Within University of Toronto’s International Pharmacy Graduate Program
   Janet Sio, Diem Cong & Karen Elaine Edge
   International Pharmacy Graduate Program, Faculty of Pharmacy, University of Toronto
3. Edu/Teach No. 3: Electronic portfolios: a novel approach for assessing learning outcomes.
   Ingrid V. Price, Jennifer A. Shabbits, Marion L. Pearson, Lynda M. Eccott
   Faculty of Pharmaceutical Sciences, University of British Columbia

4. Edu/Teach No. 4: Investigating the ‘Future’ of Pharmacy: the professional maturation and training of nascent pharmacists at one Canadian faculty of pharmacy
   Jennifer D. Beales and Zubin Austin Leslie Dan
   Faculty of Pharmacy, University of Toronto
5. Edu/Teach No. 5: Investigating socio-cultural awareness in pharmacy curricula: The role of case examples
   Jennifer D. Beales
   Leslie Dan Faculty of Pharmacy, University of Toronto
6. Edu/Teach No. 6: Evaluating First Year CAPS-I – Cases in Pharmaceutical Sciences: Educational successes and challenges
   Ingrid Price
   Faculty of Pharmaceutical Sciences, University of British Columbia
7. Edu/Teach No. 7: Characterization and analysis of direct observation forms completed by preceptors during final year experiential rotations
   Andrea J. Cameron, Lesley A. Lavack Leslie Dan
   Faculty of Pharmacy, University of Toronto
8. Edu/Teach No. 8: Experiences with collaborative practice among pharmacy and nutrition students assessing a standardized patient
   Roy Dobson, Jeff Taylor, Jane Cassidy, Doreen Walker
   College of Pharmacy and Nutrition, University of Saskatchewan Study
9. Edu/Teach No. 9: Feasibility of a web-based therapeutics course – a pilot evaluation
   Heather R Kertland^1,2, Natalie R Kennie^1,2, Lori A May¹, Thomas ER Brown^1,3
   Leslie Dan Faculty of Pharmacy, University of Toronto¹, St Michael’s Hospital², Sunnybrook and Women’s College Health Science Centre³
10. Edu/Teach No. 10: Pilot trial of online training of evidence-based practice within the pharmacy curriculum at the Université de Montréal
    Geneviève Gauthier¹, Daniel J. G. Thirion², Marie-France Beauchesne², Lucie Blais², and Claudine Laurier^{2
    1}Department of Educational Psychology, McGill University; ²Faculté de pharmacie, Université de Montréal
11. Edu/Teach No. 11: Re-structuring of pathophysiology and therapeutics in the Doctor of Pharmacy program
    Thomas ER Brown¹, Clarence Chant², Artemis Diamantorous¹, Linda D Dresser³, Heather R Kertland², Debora W Kwan⁴
    Leslie Dan Faculty of Pharmacy University of Toronto, Sunnybrook and Women’s College Health Science Centre¹, St Michael’s Hospital², Mount Sinai Hospital³, University Health Network⁴
12. Edu/Teach No. 12: Development of a first year community practice experiential program.
    Debra M. Moy, Michael R. Heffer
    Leslie Dan Faculty of Pharmacy, University of Toronto
13. Edu/Teach No. 13: An objective competency level-based method to assess student performance in experiential training.
    Christopher J. Turner, Ralph Altiere, Larry Clark, Carrie Maffeo and Connie Valdez
    University of Colorado Health Sciences Center School of Pharmacy
14. Edu/Teach No. 14: The integrated laboratory network pilot project: a virtual approach to teaching pharmaceutical analysis
    Simon P. Albon¹, Devon A. Cancilla^{2
    1}Faculty of Pharmaceutical Sciences, University of British Columbia, ²Scientific Technical Services, Western Washington University
15. Edu/Teach No. 15: An interfaculty pain curriculum for health professional students: an evaluation
    Lalitha Raman-Wilms¹, Judith Hunter², Judy Watt-Watson⁴, Leila Lax³, Glenn Regehr³, Larry Librach³, Peter Pennefather^{1
    1}Leslie Dan Faculty of Pharmacy, ²Department of Physical Therapy, ³Faculty of Medicine, ⁴Faculty of Nursing, University of Toronto

Pharmacy Practice Research

1. PPR No. 1: Evaluation of pharmacist practice in an interdisciplinary primary care team-based setting: Implications for pharmacy education
   Jana M. Bajcar^1,2, Natalie Kennie^1,2, Tom Einarson^{1
   1}Leslie Dan Faculty of Pharmacy, University of Toronto; ²Department of Family and Community Medicine, St. Michael’s Hospital
2. PPR No. 2: Involvement of a community pharmacist research network in evaluating outcomes of bisphosphonate therapy
   Judith A. Soon, Mary H.H. Ensom, D.W. Fielding, Marc Levine, James P. McCormack, Selena M. Santi
   Collaboration for Outcomes Research and Evaluation (CORxE), Faculty of Pharmaceutical Sciences, University of British Columbia
3. PPR No. 3: Drug utilization review (DUR) for the treatment of asthma
   Joëlle Mimeault, Diane Blais
   Conseil du médicament, Direction du suivi et de l'utilisation optimale
4. PPR No. 4: The provision and reimbursement of home care services by community pharmacists in Canada
   Jennifer Alissa Lawrence¹ and A. Kirsten Woodend^{2
   1}University of Saskatchewan, ²Director, Research, CPhA
5. PPR No. 5: Pictographic instructions for medications: Do other cultures interpret them accurately?
   Zahra Sadikali¹, LCol Régis Vaillancourt², John B. Collins³, Rosemin Kassam^{1
   1}Faculty of Pharmaceutical Sciences, University of British Columbia; ²Directorate of Medical Policy, Pharmacy Policy and Standards, The Canadian Forces; ³Department of Education Studies, University of British Columbia
6. PPR No. 6: Community-based warfarin co-prescribing and point of care INR testing
   Wendy A. Leong,* and London Drugs Anticoagulation Team^# {Jenny Chiang, Daniel Choi, Nelson Costa, Sanja Ivankovic, Allen Jang, Cecilia Lee, Winnie Lee, Joyce Tan, Robert Tong, John Tse, Annie Wang, Grace Yeung}^#
   Burnaby Research* & University of British Columbia*

Social and Administrative Research

1. Soc Admin No. 1: Hot on the Net: pharmaceutical policy/PDAs
   Timothy Rees, BSc and Elizabeth Foy
   College of Pharmacy, Dalhousie University